Chemically induced tubal occlusion in the human female using intrauterine instillation of quinacrine.
نویسندگان
چکیده
94 Mora, G., Faundes, A. and Pastore, U. Clinical evaluation of an oral progestin contraceptive, R 2323, 5 mg, administered at weekly intervals. Contraception 10: 145-l 58 t 1974). Tredway, D.R. and Mishell, D.R., Jr. Effect of a once weekly oral contraceptive upon gonadotrophin and gonadal steroid levels. Contraception 10: 159-l 70 (1974). Johansson, E.D.B. Progesterone levels in peripheral plasma during the luteal phase of the normal human menstrual cycle measured by a rapid competitive protein binding technique. Acta endocr (Kbh) 61: 592-606 (1969). Hotchkiss, J., Atkinson, L.E. and Knobil, E. Time course of serum estrogen and luteinizing hormone (LH) concentrations during the menstrual cycle of the rhesus monkey. Endocrinology 89: 177-l 83 (197 1). Edqvist, L.E. and Johansson, E.D.B. Radioimmunoassay of estrone and estradiol in human and bovine peripheral plasma. Acta endocr (Kbh) 7 1: 7 16-73 1 (1972). Larsson-Cohn, U., Johansson, E.D.B. and Gemzell, C. Effects of continuous daily administration of 0.5 mg of norethindrone on the plasma levels of progesterone and on the urinary excretion of luteinizing hormone and total estrogens. Acta endocr (Kbh) 63: 216-224 (1970). Larsson-Cohn, U., Johansson, E.D.B. and Gemzell, C. Effects of continuous administration of 0.3 mg of norethindrone on the plasma levels of progesterone and on the urinary excretion of pregnanediol and total estrogens. Acta endocr (Kbh) 64: 38-46 (1970). Johansson, E.D.B. and Luukkainen, T. Personal communication. Mora, G. Personal communication.
منابع مشابه
Association for Voluntary Surgical Contraception: a technical statement on quinacrine pellets for nonsurgical female sterilization.
For many years, researchers have been seeking nonsurgical methods for female sterilization because these methods may be safer, simpler, cheaper, and quicker than conventional techniques, and may require a lower level of skill to deliver. Various investigators have explored using intrauterine instillation of quinacrine for tubal occlusion. Until recently, reports of quinacrine use for nonsurgica...
متن کاملNonsurgical female sterilization: comparison of intrauterine application of quinacrine alone or in combination with ibuprofen.
In many parts of the world, sterilization has become the leading method of fertility control (1). The need to make this procedure s impler , safer , and less expensive-and thereby more acceptable, even in countr ies with limited surgical facilities-is well recognized. Consequently, in the past three decades, various chemicals have been used to accomplish tubal occlusion through transcervical in...
متن کاملEfficacy and safety of repeated transcervical quinacrine pellet insertions for female sterilization.
OBJECTIVE To investigate the rates of tubal occlusion, pregnancy, and side effects of repeated, monthly transcervical insertions of 252 mg quinacrine as pellets. DESIGN Clinical trial among 159 reproductive age women receiving two monthly transcervical insertions of 252 mg of quinacrine followed by hysterosalpingograms (HSGs) 1 month after last insertion and an additional monthly insertion am...
متن کاملHuman fertility control by transvaginal application of quinacrine on the fallopian tube.
The development of a technic for noniurgical steri l ization having acceptable clinical effectiveness and a minimum of undesirable side effects is one of the principal &jectiVeS of physicians who are concerned shout the demographic problems of the world. As noted by Corfman,l who recently reviewed the relevant historic aspects, transvaginal sterilization technics have been studied for more than...
متن کاملLack of tubal occlusion by intrauterine quinacrine and tetracycline in the primate.
The effects of slow- and fast-releasing quinacrine pellets and tetracycline tablets on the genital tracts of 20 cynomolgus monkeys was evaluated. After surgical implantation of the pellets, the primates were observed for three months. No signs of toxic effects to the drugs were observed during the three-month period and on autopsy. Histopathological evaluation of the fallopian tubes, cervix, ov...
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عنوان ژورنال:
- Contraception
دوره 12 1 شماره
صفحات -
تاریخ انتشار 1975